SCHEMBL345903

SCHEMBL345903

C=C(C)C(=O)OCCCCCCCCCCCOP(=O)(O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
LPAR3 Q9UBY5 8/20 0.53
LPAR2 Q9HBW0 6/20 0.53
LPAR1 Q92633 4/20 0.53
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 1/20 0.40
BTN3A1 O00481 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617843 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL1653308 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL15795 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL346866 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL15166 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345787 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345385 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL346923 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL1651991 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345072 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782599-A1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GmbH (DE) 2021-02-24 EP claimed
EP-2492289-B1 POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY NORITAKE DENTAL INC (JP) 2020-03-18 EP claimed
US-9333148-B2 Polymerizable composition and dental material KURARAY NORITAKE DENTAL INC. (JP) 2016-05-10 US claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
US-6512068-B1 Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of KURARAY CO., LTD. (JP) 2003-01-28 US claimed
US-12441821-B2 (Meth)acrylate and use thereof MITSUI CHEMICALS, INC. (JP) 2025-10-14 US disclosed
US-20250122315-A1 (METH)ACRYLATE AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2025-04-17 US disclosed
CN-119816330-A Radiopaque monomers and embolic microspheres containing same 法国加栢 2025-04-11 CN disclosed
EP-3719043-B1 (METH)ACRYLATE, MONOMER COMPOSITION, DENTAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS INC (JP) 2024-11-13 EP disclosed
EP-3603606-B1 ADHESIVE MONOMER FOR DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2024-11-13 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
US-4650847-A DENTISTRY KURARAY CO., LTD. (JP) 1987-03-17 US disclosed
US-4612384-A Phosphate monoester adhesive composition KURARAY CO., LTD. (JP) 1986-09-16 US disclosed
EP-0074708-B1 ADHESIVE COMPOSITION KURARAY CO., LTD. (JP) 1986-02-19 EP disclosed
US-4539382-A ACRYLIC PHOSPHORIC ACID DERIVATIVE KURARAY CO., LTD. (JP) 1985-09-03 US disclosed
EP-0074708-A2 Adhesive composition KURARAY CO., LTD. (JP) 1983-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL TSHR 4710/4885LPAR3 2934/4885LPAR2 3391/4885
US-20250122315-A1 (METH)ACRYLATE AND USE THEREOF TST, MMAB, BHMT2 TSHR 2952/4885LPAR3 4688/4885LPAR2 4856/4885
US-12441821-B2 (Meth)acrylate and use thereof TST, MMAB, BHMT2 TSHR 2952/4885LPAR3 4688/4885LPAR2 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.