Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30617843 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL1653308 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL15795 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL346866 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL15166 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL345385 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL346923 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL1651991 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL345903 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB | |
| SCHEMBL345072 | 1.00 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | claimed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | claimed |
| EP-2492289-B1 | POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | KURARAY NORITAKE DENTAL INC (JP) | 2020-03-18 | — | — | EP | claimed |
| US-9333148-B2 | Polymerizable composition and dental material | KURARAY NORITAKE DENTAL INC. (JP) | 2016-05-10 | — | — | US | claimed |
| US-8329845-B2 | Divided redox-curing type composition | KURARAY NORITAKE DENTAL INC. (JP) | 2012-12-11 | — | — | US | claimed |
| US-6984673-B2 | Dental cement composition | KURARAY CO., LTD. (JP) | 2006-01-10 | — | — | US | claimed |
| US-12441821-B2 | (Meth)acrylate and use thereof | MITSUI CHEMICALS, INC. (JP) | 2025-10-14 | — | — | US | disclosed |
| US-20250122315-A1 | (METH)ACRYLATE AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2025-04-17 | — | — | US | disclosed |
| EP-3719043-B1 | (METH)ACRYLATE, MONOMER COMPOSITION, DENTAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PRODUCTION METHOD THEREOF | MITSUI CHEMICALS INC (JP) | 2024-11-13 | — | — | EP | disclosed |
| EP-3603606-B1 | ADHESIVE MONOMER FOR DENTAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2024-11-13 | — | — | EP | disclosed |
| WO-2024150826-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-07-18 | — | — | WO | disclosed |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | KURARAY CO., LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| US-20240199494-A1 | ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF | Kuraray Noritake Dental lnc. (JP) | 2024-06-20 | — | — | US | disclosed |
| EP-1269967-A1 | Dental composition kit | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-20020198284-A1 | Adhesive composition | KURARAY CO. LTD, (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1262530-A1 | ADHESIVE COMPOSITION | KURARAY CO., LTD. (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-20020061938-A1 | Bonding composition | KURARAY CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6387979-B1 | FOR TOOTH TISSUE | KURARAY CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1101484-A2 | Dental fillers | KABUSHIKI KAISHA SHOFU (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1051961-A1 | Bonding compositions for dental use | KURARAY CO., LTD. (JP) | 2000-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885LPAR3 1042/4885LPAR2 2192/4885 |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | ARL1, ASH2L, VCL | TSHR 4710/4885LPAR3 2934/4885LPAR2 3391/4885 |
| US-20250122315-A1 | (METH)ACRYLATE AND USE THEREOF | TST, MMAB, BHMT2 | TSHR 2952/4885LPAR3 4688/4885LPAR2 4856/4885 |
| US-12441821-B2 | (Meth)acrylate and use thereof | TST, MMAB, BHMT2 | TSHR 2952/4885LPAR3 4688/4885LPAR2 4856/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885LPAR3 1042/4885LPAR2 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.