SCHEMBL3468883

SCHEMBL3468883

CCc1c(C)cccc1Cc1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
USP2 O75604 1/20 0.40
SHBG P04278 1/20 0.39
KMT2A Q03164 1/20 0.39
AR P10275 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
CHRM2 P08172 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36
MAPT P10636 1/20 0.36
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787756 0.94 GABRA1 (0.46) TAAR1GABRA1GABRB2SHBGCYP3A4
SCHEMBL6546938 0.90 GABRA1 (0.45) TAAR1GABRA1GABRB2SHBGKMT2A
SCHEMBL2844544 0.87 USP2 (0.45) TAAR1USP2KMT2AARCYP3A4
SCHEMBL9746190 0.86 TP53 (0.44) KMT2ACYP3A4CYP2C19TSHR
SCHEMBL9488152 0.85 SHBG (0.44) TAAR1GABRA1GABRB2SHBGKMT2A
SCHEMBL6545944 0.84 TAAR1 (0.44) TAAR1GABRA1GABRB2USP2KMT2A
SCHEMBL8086373 0.82 TAAR1 (0.48) TAAR1USP2KMT2AARCHRM2
SCHEMBL3258673 0.82 GABRA1 (0.48) TAAR1GABRA1GABRB2SHBGCYP3A4
SCHEMBL169506 0.82 GABRA1 (0.48) TAAR1GABRA1GABRB2SHBGCYP3A4
SCHEMBL2090458 0.82 TAAR1 (0.56) TAAR1KMT2AARCHRM2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010047432-A1 REMOVABLE LENS PROTECTION COATING AGENT COMPRISING WATER-DISPERSION POLYURETHANE GU JA EUN (KR) 2010-04-29 WO disclosed