SCHEMBL9488152

SCHEMBL9488152

CCc1cccc(C)c1CC.CCc1ccccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.44
TAAR1 Q96RJ0 2/20 0.43
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
PTGS2 P35354 2/20 0.41
PTGS1 P23219 1/20 0.41
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CTBP2 P56545 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
ALOX12 P18054 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CHRM2 P08172 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258673 0.93 GABRA1 (0.48) SHBGTAAR1GABRA1GABRB2PTGS2
SCHEMBL169506 0.93 GABRA1 (0.48) SHBGTAAR1GABRA1GABRB2PTGS2
Ammonia Solution, Strong SCHEMBL7055042 0.91 GABRA1 (0.46) SHBGTAAR1GABRA1GABRB2PTGS2
Methylamine SCHEMBL27931104 0.91 GABRA1 (0.46) SHBGTAAR1GABRA1GABRB2PTGS2
Ammonia Solution, Strong SCHEMBL150658 0.91 GABRA1 (0.46) SHBGTAAR1GABRA1GABRB2PTGS2
Diethylamine SCHEMBL6284503 0.88 CYP1A2 (0.40) SHBGTAAR1GABRA1GABRB2PTGS2
SCHEMBL40576 0.86
SCHEMBL5489439 0.86 TAAR1 (0.54) SHBGTAAR1GABRA1GABRB2PTGS2
SCHEMBL29458957 0.86
SCHEMBL3468883 0.85 TAAR1 (0.42) SHBGTAAR1GABRA1GABRB2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5177286-A Selective production of a p-alkyltoluene or 4,4'-alkylmethylbiphenyl AMOCO CORPORATION (US) 1993-01-05 US disclosed