Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 7/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346038 | 0.82 | TTR (0.35) | BACE1KMT2A | |
| SCHEMBL1424585 | 0.82 | KMT2A (0.34) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL7874033 | 0.77 | CA12 (0.30) | CA12CA1CA2CA9CA14 | |
| SCHEMBL454678 | 0.77 | ALDH1A1 (0.40) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL1425447 | 0.71 | ALDH1A1 (0.39) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL30745045 | 0.71 | TAS1R3 (0.36) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL20943921 | 0.71 | TAS1R3 (0.36) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL2018841 | 0.71 | KDM4E (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16114710 | 0.71 | SYK (0.37) | CA12CA1CA2CA9CA14 | |
| Hydrochloric Acid SCHEMBL11456791 | 0.71 | HRH4 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |