Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 1.00 |
| ▸ | PDE6A | P16499 | 1/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467938 | 0.81 | PDE5A (0.67) | PDE5APDE6APDE1BPDE3APDE10A | |
| SCHEMBL3473549 | 0.80 | PDE5A (0.67) | PDE5APDE6APDE1BPDE3APDE10A | |
| SCHEMBL3469571 | 0.77 | PDE5A (0.63) | PDE5APDE6APDE1BPDE3AGRIA1 | |
| SCHEMBL3467028 | 0.75 | PDE5A (0.60) | PDE5APDE6APDE1BPDE3AALDH1A1 | |
| SCHEMBL3467020 | 0.75 | PDE5A (0.60) | PDE5APDE6APDE1BPDE3AGRIA1 | |
| SCHEMBL3466485 | 0.74 | GRIA1 (0.60) | PDE5APDE6APDE1BPDE3AGRIA1 | |
| SCHEMBL3467072 | 0.74 | PDE5A (0.59) | PDE5APDE6APDE1BPDE3AGRIA1 | |
| SCHEMBL2486922 | 0.74 | PDE5A (0.58) | PDE5APDE6APDE1BPDE3APDE10A | |
| SCHEMBL2487528 | 0.74 | GRIA1 (0.64) | PDE5APDE6APDE1BPDE3AGRIA1 | |
| SCHEMBL6937711 | 0.73 | PDE5A (0.56) | PDE5APDE6APDE1BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |