SCHEMBL3469331

SCHEMBL3469331

c1ccc2sc(-c3ccsc3)nc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.64
NPC1 O15118 7/20 0.64
KDM4E B2RXH2 6/20 0.64
MAPT P10636 3/20 0.57
APP P05067 3/20 0.57
ALDH1A1 P00352 3/20 0.57
LMNA P02545 2/20 0.57
GLA P06280 2/20 0.57
GAA P10253 2/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
L3MBTL1 Q9Y468 3/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NFKB1 P19838 2/20 0.53
NFKB2 Q00653 2/20 0.53
RELA Q04206 2/20 0.53
PKM P14618 1/20 0.53
ILK Q13418 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25028306 0.81 KDM4E (0.43) RAB9ANPC1KDM4EMAPTAPP
SCHEMBL366824 0.81 RAB9A (0.81) RAB9ANPC1KDM4EMAPTAPP
SCHEMBL29474819 0.81 RAB9A (0.81) RAB9ANPC1KDM4EMAPTAPP
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.79 RAB9A (0.75) RAB9ANPC1KDM4EMAPTAPP
SCHEMBL13053014 0.79 RAB9A (0.69) RAB9ANPC1KDM4EMAPTAPP
SCHEMBL24295138 0.79 RAB9A (0.79) RAB9ANPC1KDM4EMAPTAPP
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.79 RAB9A (0.75) RAB9ANPC1KDM4EMAPTAPP
2-Phenylbenzo[D]Thiazole SCHEMBL27789684 0.79 RAB9A (0.64) RAB9ANPC1KDM4EMAPTAPP
SCHEMBL28560824 0.78 NPC1 (0.50) RAB9ANPC1KDM4EMAPTALDH1A1
SCHEMBL827403 0.78 RAB9A (0.67) RAB9ANPC1KDM4EMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104761536-B Method of synthesizing 2-substituted benzothiazole-type derivative 内蒙古工业大学 2017-05-10 CN claimed
CN-104761536-A Method of synthesizing 2-substituted benzothiazole-type derivative UNIV INNER MONGOLIA TECHNOLOGY 2015-07-08 CN claimed
CN-105884714-B A kind of green syt 2- replaces the method for benzo thiazole derivative 内蒙古工业大学 2018-11-23 CN disclosed
CN-104761536-B Method of synthesizing 2-substituted benzothiazole-type derivative 内蒙古工业大学 2017-05-10 CN disclosed
CN-105884714-A Method for realizing green synthesis of 2-substituted benzothiazole derivatives 内蒙古工业大学 2016-08-24 CN disclosed
CN-104761536-A Method of synthesizing 2-substituted benzothiazole-type derivative UNIV INNER MONGOLIA TECHNOLOGY 2015-07-08 CN disclosed
US-8969127-B2 Apparatus for and method of fabricating an electronic device by transfer of material onto a substrate NOVALIA LTD (GB) 2015-03-03 US disclosed
EP-2206171-B1 METHOD OF FABRICATING AN ELECTRONIC DEVICE NOVALIA LTD (GB) 2014-05-14 EP disclosed
US-20100295028-A1 Method of Fabricating an Electronic Device NOVALIA LTD (GB) 2010-11-25 US disclosed
EP-2206171-A1 METHOD OF FABRICATING AN ELECTRONIC DEVICE Novalia Ltd (GB) 2010-07-14 EP disclosed
WO-2009050516-A1 METHOD OF FABRICATING AN ELECTRONIC DEVICE NOVALIA LTD (GB) 2009-04-23 WO disclosed