SCHEMBL3469355

SCHEMBL3469355

CCc1ccc(/C=C/c2cnc(/C=C/c3ccc(CC)cc3)cn2)cc1.Cc1ccc(/C=C/c2cnc(/C=C/c3ccc(C)cc3)cn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
ALOX5 P09917 2/20 0.47
PTGS1 P23219 2/20 0.47
PTGS2 P35354 2/20 0.47
DHFR P00374 2/20 0.43
KDM4E B2RXH2 5/20 0.41
HPGD P15428 3/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TUBB1 Q9H4B7 1/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NFE2L2 Q16236 2/20 0.41
ALDH1A1 P00352 3/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3469357 1.00 MAPT (0.50) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL317844 0.93 MAPT (0.56) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL317843 0.93 MAPT (0.56) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL317835 0.87 MAPT (0.62) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL317834 0.87 MAPT (0.62) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL5651348 0.85 DHFR (0.51) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL5651345 0.85 DHFR (0.51) MAPTALOX5PTGS1PTGS2DHFR
SCHEMBL6546965 0.85 PTGS1 (0.60) ALOX5PTGS1PTGS2DHFRRAB9A
SCHEMBL28779438 0.85 PTGS1 (0.60) ALOX5PTGS1PTGS2DHFRRAB9A
SCHEMBL29086916 0.85 PTGS1 (0.60) ALOX5PTGS1PTGS2DHFRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262032-A2 Organic electroluminescence device and its manufacturing method Idemitsu Kosan Co., Ltd. (JP) 2010-12-15 EP disclosed
US-20030075714-A1 Organic electroluminescence device and method of manufacturing same IDEMITSU KOSAN CO., LTD. (JP) 2003-04-24 US disclosed
US-6469438-B2 Organic electroluminescence device with prescribed optical path length IDEMITSU KOSAN CO., LTD. (JP) 2002-10-22 US disclosed
US-20010000943-A1 Organic electroluminescence device and method of manufacturing same IDEMITSU KOSAN CO., LTD. 2001-05-10 US disclosed
EP-1093322-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ITS MANUFACTURING METHOD Idemitsu Kosan Co., Ltd. (JP) 2001-04-18 EP disclosed
EP-0563811-A1 Silanamine derivative and process for the production thereof, and organical EL device using the said silanamine derivative IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-10-06 EP disclosed