SCHEMBL5651348

SCHEMBL5651348

CCc1ccc(C=Cc2ccc(C=Cc3ccc(CC)cc3)nc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.51
KDM4E B2RXH2 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALOX5 P09917 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
MAPT P10636 5/20 0.47
TUBB1 Q9H4B7 1/20 0.46
HTR2A P28223 1/20 0.40
KCNH2 Q12809 1/20 0.40
MCHR1 Q99705 2/20 0.40
MAOB P27338 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5651345 1.00 DHFR (0.51) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL317844 0.92 MAPT (0.56) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL317843 0.92 MAPT (0.56) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL3469355 0.85 MAPT (0.50) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL3469357 0.85 MAPT (0.50) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL8972152 0.84 KDM4E (0.54) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL9148560 0.84 KDM4E (0.54) DHFRKDM4EL3MBTL1ALOX5PTGS1
SCHEMBL6546261 0.82 ALOX5 (0.63) DHFRKDM4EALOX5PTGS1PTGS2
SCHEMBL16853122 0.82 ALOX5 (0.63) DHFRKDM4EALOX5PTGS1PTGS2
SCHEMBL9026432 0.82 ALOX5 (0.63) DHFRKDM4EALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070229648-A1 EXPOSURE DEVICE AND IMAGE FORMING APPARATUS USING THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-10-04 US disclosed
US-6833667-B2 Organic electroluminescence element and image forming apparatus or portable terminal unit using thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-12-21 US disclosed
US-20030164679-A1 Organic electroluminescence element and image forming apparatus or portable terminal unit using thereof JOLED INC (JP) 2003-09-04 US disclosed