Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473549 | 0.82 | PDE5A (0.67) | PDE5APDE6APDE1BPDE3AMEN1 | |
| SCHEMBL3467929 | 0.75 | DYRK3 (0.57) | FLT3MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL3469421 | 0.72 | FLT3 (0.54) | FLT3 | |
| SCHEMBL5404980 | 0.72 | MAPT (0.41) | PDE5APDE6APDE1BPDE3AKMT2A | |
| SCHEMBL5404986 | 0.70 | FLT3 (0.52) | FLT3CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL3470436 | 0.68 | TTK (0.52) | FLT3 | |
| SCHEMBL10075921 | 0.68 | HTR7 (0.54) | HSD17B10DRD2HTR1AHTR7LMNA | |
| SCHEMBL7497109 | 0.68 | DRD2 (0.59) | DRD2HTR2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3470660 | 0.68 | FYN (0.54) | PDE5APDE6APDE1BPDE3AFLT3 | |
| SCHEMBL1193073 | 0.68 | DRD2 (0.75) | MEN1KMT2ACYP1A2CYP2C19DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |