Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.67 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558531 | 0.80 | PSMB8 (0.44) | PSMB8MAP2K1KCNMA1HTTTRPA1 | |
| SCHEMBL20479488 | 0.80 | PSMB8 (0.65) | PSMB8KCNMA1PARP1DYRK1ACNR2 | |
| SCHEMBL3888532 | 0.80 | PSMB8 (0.65) | PSMB8GAA | |
| SCHEMBL6427935 | 0.80 | PARP1 (0.53) | PSMB8MAP2K1KCNMA1HTTPARP1 | |
| SCHEMBL9173518 | 0.80 | PSMB8 (0.65) | PSMB8KCNMA1PARP1GAA | |
| SCHEMBL20305276 | 0.77 | PSMB8 (0.49) | PSMB8MAP2K1KCNMA1HTTPARP1 | |
| SCHEMBL15558409 | 0.76 | PSMB8 (0.41) | PSMB8MAP2K1KCNMA1PARP1CLK1 | |
| SCHEMBL20305418 | 0.75 | PIN1 (0.49) | PSMB8PARP1CNR2 | |
| SCHEMBL8801850 | 0.74 | NUDT1 (0.55) | PSMB8KCNMA1 | |
| SCHEMBL31588409 | 0.74 | NUDT1 (0.55) | PSMB8KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978655-A | Benzimidazole structure covalent triazine frame porous organic polymer and preparation method and application thereof | 宁德师范学院 | 2024-11-19 | — | — | CN | claimed |
| CN-118978655-A | Benzimidazole structure covalent triazine frame porous organic polymer and preparation method and application thereof | 宁德师范学院 | 2024-11-19 | — | — | CN | disclosed |
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-04-26 | — | — | US | disclosed |
| US-8106393-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-01-05 | — | — | US | disclosed |
| US-7919770-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20110015388-A1 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | UNITED STATES DEPARTMENT OF ENERGY | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | PSMB8 4575/4885MAP2K1 1788/4885KCNMA1 472/4885 |
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | PSMB8 4575/4885MAP2K1 1788/4885KCNMA1 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.