Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469918 | 0.86 | ALDH1A1 (0.38) | EPHX1ALDH1A1TP53GAANPSR1 | |
| SCHEMBL14890929 | 0.68 | ALDH1A1 (0.42) | EPHX1ALDH1A1GAANPSR1KDM4E | |
| SCHEMBL3935214 | 0.68 | EPHX1 (0.44) | EPHX1ALDH1A1NPSR1LMNA | |
| SCHEMBL8038274 | 0.67 | EPHX1 (0.39) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL1782429 | 0.67 | RAB9A (0.41) | EPHX1ALDH1A1NPSR1LMNAPMP22 | |
| SCHEMBL5197831 | 0.65 | ALDH1A1 (0.37) | EPHX1ALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL1785494 | 0.65 | ALDH1A1 (0.54) | EPHX1ALDH1A1NPSR1KDM4ETSHR | |
| SCHEMBL6893065 | 0.65 | EPHX1 (0.48) | EPHX1ALDH1A1TP53NPSR1KDM4E | |
| SCHEMBL660922 | 0.65 | ALDH1A1 (0.54) | EPHX1ALDH1A1NPSR1KDM4ETSHR | |
| SCHEMBL4200004 | 0.64 | LMNA (0.46) | LMNAPMP22TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139866-A2 | CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION | KRKA, D.D., Novo Mesto (SI) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008129077-A2 | CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION | KRKA, D.D. NOVO MESTO (SI) | 2008-10-30 | — | — | WO | disclosed |