Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808829 | 0.86 | MEN1 (0.55) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29903394 | 0.85 | MAPT (0.61) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL30808838 | 0.84 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL30808836 | 0.83 | KMT2A (0.67) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL29903249 | 0.81 | RAB9A (0.62) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL29903328 | 0.80 | CYP2D6 (0.60) | KMT2AMEN1NPC1POLBCYP2D6 | |
| SCHEMBL30808831 | 0.77 | NPC1 (0.62) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL21441798 | 0.77 | KMT2A (0.74) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL29831996 | 0.77 | KMT2A (0.74) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL30808841 | 0.76 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100086921-A1 | GENETIC SUSCEPTIBILITY VARIANTS OF TYPE 2 DIABETES MELLITUS | SAGA INVESTMENTS LLC | 2010-04-08 | — | — | US | disclosed |