Taltrimide

Taltrimide

SCHEMBL347001

CC(C)NS(=O)(=O)CCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.48
CASP3 P42574 2/20 0.46
GLS O94925 1/20 0.45
MAOB P27338 4/20 0.43
ALDH1A1 P00352 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taltrimide SCHEMBL29866257 1.00 NPSR1 (0.48) NPSR1CASP3GLSMAOBALDH1A1
Taltrimide SCHEMBL4621819 0.93 NPSR1 (0.43) NPSR1CASP3GLSMAOBALDH1A1
SCHEMBL3757316 0.82 GLS (0.49) CASP3GLSCA1CA2CA4
SCHEMBL28967744 0.82 CASP3 (0.44) CASP3GLSCA1CA2CA4
SCHEMBL6029821 0.78 GLS (0.45) CASP3GLSCA1CA2CA4
SCHEMBL3759156 0.78 CASP3 (0.49) CASP3GLSALDH1A1CA1CA2
SCHEMBL11014716 0.77 KDM4E (0.49) GLSALDH1A1CA9
SCHEMBL1306411 0.76 GLS (0.53) NPSR1CASP3GLSCA1CA2
SCHEMBL18605556 0.76 GLS (0.42) CASP3GLSMAOBCA1CA2
SCHEMBL20111946 0.75 CASP3 (0.47) CASP3GLSCA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-3377054-B1 HOMOTAURINE-ENRICHED COMPOSITIONS AND METHODS OF USE FOR ANIMAL HEALTH FB MARIA SRL (IT) 2024-12-11 EP disclosed
US-12133838-B2 Homotaurine-enriched compositions and methods of use for animal health FB MARIA SRL (IT) 2024-11-05 US disclosed
US-12042566-B2 Formulations of homotaurines and salts thereof CONFLUENCE PHARMACEUTICALS, LLC (US) 2024-07-23 US disclosed
US-20220184005-A1 HOMOTAURINE-ENRICHED COMPOSITIONS AND METHODS OF USE FOR ANIMAL HEALTH FB MARIA SRL (IT) 2022-06-16 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11224579-B2 Homotaurine-enriched compositions and methods of use for animal health FB MARIA SRL (IT) 2022-01-18 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-20050002865-A1 Diagnostic/therapeutic agents AMERSHAM HEALTH AS (NO) 2005-01-06 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 NPSR1 2630/4885CASP3 719/4885GLS 1845/4885
US-20050002865-A1 Diagnostic/therapeutic agents FUS, HNRNPF, HNRNPR NPSR1 2468/4885CASP3 1043/4885GLS 1136/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 NPSR1 2359/4885CASP3 973/4885GLS 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.