Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471172 | 0.90 | KDM4E (0.61) | KDM4EPOLBHSD17B10SMN1; SMN2BPTF | |
| SCHEMBL4734795 | 0.88 | KDM4E (1.00) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL23489254 | 0.87 | KDM4E (0.56) | KDM4EPOLBHSD17B10SMN1; SMN2BPTF | |
| SCHEMBL3471733 | 0.78 | PKM (0.60) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL27793485 | 0.76 | KDM4E (0.50) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL6383531 | 0.76 | KDM4E (0.78) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL1012737 | 0.76 | KDM4E (0.78) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL13753820 | 0.75 | KDM4E (0.65) | KDM4EPOLBUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL267613 | 0.75 | KDM4E (0.49) | KDM4EPOLBHSD17B10SMN1; SMN2GAA | |
| SCHEMBL8639986 | 0.74 | BPTF (0.56) | KDM4ESMN1; SMN2BPTFHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147102-A1 | SYNTHETIC METHOD FOR 6,7-SUBSTITUENTS-4-ANILINE QUINAZOLINE | 翔真生物科技股份有限公司 (CN) | 2011-12-01 | — | — | WO | disclosed |
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | KDM4E 2145/4885POLB 2315/4885USP2 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.