Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470397 | 0.89 | HTT (0.48) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL13344409 | 0.87 | KDM4E (0.43) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3466882 | 0.85 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3466582 | 0.84 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3466147 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3467710 | 0.83 | KDM4E (0.46) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3466292 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHSD17B10GPR55 | |
| SCHEMBL3465801 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHSD17B10SMO | |
| SCHEMBL3467187 | 0.79 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHSD17B10SMO | |
| SCHEMBL23009014 | 0.79 | ABCB1 (0.46) | ALDH1A1MAPTKDM4EHSD17B10GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |