Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466882 | 0.83 | KDM4E (0.48) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3466582 | 0.82 | KDM4E (0.48) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3470397 | 0.82 | HTT (0.48) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3466147 | 0.81 | ALDH1A1 (0.55) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3467710 | 0.81 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4EGPR55SMO | |
| SCHEMBL13344409 | 0.81 | KDM4E (0.43) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL23008972 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EGPR55SMO | |
| SCHEMBL3466292 | 0.79 | ALDH1A1 (0.56) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3470519 | 0.79 | ALDH1A1 (0.43) | ABCB1ALDH1A1HSD17B10KDM4EGPR55 | |
| SCHEMBL3465801 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4ESMOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210047278-A1 | E3 UBIQUITIN LIGASE AGONISTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE E3 UBIQUITIN LIGASE AGONISTS, RELATED METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047278-A1 | E3 UBIQUITIN LIGASE AGONISTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE E3 UBIQUITIN LIGASE AGONISTS, RELATED METHODS OF USE | UBE3A, NEDD4, ADRM1 | ABCB1 1713/4885ALDH1A1 1174/4885HSD17B10 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.