Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524065 | 0.86 | LCK (0.43) | LCKCISD1BACE1PTGS2TTR | |
| Methane SCHEMBL27792691 | 0.84 | LCK (0.42) | LCKCISD1BACE1PTGS2TTR | |
| SCHEMBL29958196 | 0.78 | CYP1A1 (0.58) | ALDH5A1ABATBACE1PTGS2TTR | |
| SCHEMBL378297 | 0.78 | CYP1A1 (0.58) | ALDH5A1ABATBACE1PTGS2TTR | |
| SCHEMBL37131 | 0.78 | LCK (0.58) | ALDH5A1ABATLCKBACE1PTGS2 | |
| SCHEMBL9261197 | 0.78 | LCK (0.58) | ALDH5A1ABATLCKBACE1PTGS2 | |
| SCHEMBL4575600 | 0.78 | ALDH5A1 (0.52) | ALDH5A1ABATLCKBACE1PTGS2 | |
| SCHEMBL24445876 | 0.77 | CA12 (0.48) | LCKPTGS2RAB9AMAPT | |
| SCHEMBL8804437 | 0.77 | ALDH1A1 (0.48) | BACE1PTGS2TTRCYP1A1ALOX5 | |
| Resorcinol SCHEMBL28044421 | 0.77 | CYP3A4 (0.50) | LCKTTRALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323969-A1 | Compounds Binding to P-Selectin | ASTELLAS PHARMA EUROPE B.V. (NL) | 2010-12-23 | — | — | US | disclosed |
| US-20090062186-A1 | Compounds Binding To P-Selectin | YAMANOUCHI ERUOPE B.V. (NL) | 2009-03-05 | — | — | US | disclosed |
| EP-1527086-B1 | COMPOUNDS BINDING TO P-SELECTIN | ASTELLAS PHARMA EUROP B V (NL) | 2008-01-09 | — | — | EP | disclosed |
| US-20060217294-A1 | Compounds binding to p-selectin | YAMANOUCHI EUROPE B.V. | 2006-09-28 | — | — | US | disclosed |
| EP-1527086-A1 | COMPOUNDS BINDING TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004018502-A1 | COMPOUNDS BINDING TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062186-A1 | Compounds Binding To P-Selectin | SELP, SELPLG, SELL | ALDH5A1 3325/4885ABAT 4568/4885LCK 3554/4885 |
| US-20100323969-A1 | Compounds Binding to P-Selectin | SELP, SELPLG, SELL | ALDH5A1 3325/4885ABAT 4568/4885LCK 3554/4885 |
| US-20060217294-A1 | Compounds binding to p-selectin | SELP, SELPLG, SELL | ALDH5A1 3325/4885ABAT 4568/4885LCK 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.