SCHEMBL10486276

SCHEMBL10486276

O=C(c1ccc(Oc2ccc(O)cc2)cc1)c1ccc(-c2ccc(C(=O)c3ccc(Oc4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
KMT2A Q03164 3/20 0.64
LMNA P02545 2/20 0.64
MEN1 O00255 2/20 0.64
RAB9A P51151 2/20 0.64
ESR2 Q92731 3/20 0.62
ESR1 P03372 2/20 0.62
HPGD P15428 2/20 0.62
PKM P14618 1/20 0.62
HTT P42858 1/20 0.62
PARP10 Q53GL7 2/20 0.62
SRD5A2 P31213 2/20 0.55
ELANE P08246 1/20 0.55
HSD17B1 P14061 1/20 0.52
MAPK1 P28482 1/20 0.52
MMP2 P08253 1/20 0.52
MMP3 P08254 1/20 0.52
LTA4H P09960 2/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10486226 0.94 MAPT (0.71) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL31012104 0.94 MAPT (0.71) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL8071074 0.94 MAPT (0.71) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL3471102 0.94 MAPT (0.71) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL22295638 0.93 MEN1 (0.79) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL16425789 0.91 LMNA (0.55) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL16705546 0.91 HSD17B1 (0.69) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL5020486 0.91 LMNA (0.55) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL16425784 0.91 LMNA (0.55) MAPTKMT2ALMNAMEN1RAB9A
SCHEMBL16378244 0.91 HSD17B1 (0.69) MAPTKMT2ALMNAMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9803050-B2 Dispersant for use in synthesis of polyaryletherketones TICONA LLC (US) 2017-10-31 US disclosed
WO-2016057253-A1 DISPERSANT FOR USE IN SYNTHESIS OF POLYARYLETHERKETONES TICONA LLC (US) 2016-04-14 WO disclosed
US-20160102173-A1 Dispersant for Use in Synthesis of Polyaryletherketones TICONA LLC 2016-04-14 US disclosed
US-4837296-A REACTING AROMATIC DIHYDROXY COMPOUUNDS WITH AROMATIC DIHALOGEN COMPOUNDS IN POLAR APROTIC SOLVENTS AND ALKALI METAL CARBONATES BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0275035-A2 Process for the preparation of poly(aryl ether ketones) BASF Aktiengesellschaft (DE) 1988-07-20 EP disclosed