Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261693 | 0.76 | AKR1B1 (0.44) | FFAR4KDM4E | |
| SCHEMBL7136191 | 0.75 | APAF1 (0.41) | PPARAPPARGALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12713189 | 0.72 | PPARA (0.43) | PPARAPPARGALDH1A1L3MBTL1KDM4E | |
| SCHEMBL18585398 | 0.71 | TAAR1 (0.34) | KDM4E | |
| SCHEMBL31152890 | 0.71 | CYP1A2 (0.33) | KDM4E | |
| SCHEMBL261259 | 0.69 | TAAR1 (0.31) | — | |
| SCHEMBL2482374 | 0.69 | PPARA (0.48) | PPARAPPARGALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9780682 | 0.68 | AKR1B1 (0.52) | ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL9780678 | 0.68 | AKR1B1 (0.52) | ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL30949557 | 0.68 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254417-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090401-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |