Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657908 | 0.75 | CHRNA1 (0.46) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5855213 | 0.73 | CHRNB2 (0.44) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL123189 | 0.73 | CHRNB2 (0.44) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11938179 | 0.73 | CHRNB2 (0.44) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19809331 | 0.70 | ALDH1A1 (0.39) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4376737 | 0.68 | PNMT (0.45) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11462510 | 0.68 | CHRNB2 (0.41) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL873359 | 0.68 | CHRNB2 (0.41) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1322736 | 0.67 | CHRM2 (0.46) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13471 | 0.67 | KCNH2 (0.44) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378012-B2 | Flame retardant composition and hydrolysis-susceptible resin containing same | ICL-IP AMERICA INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20100044654-A1 | Flame Retardant Composition and Hydrolysis-Susceptible Resin Containing Same | ICL-IP AMERICA INC. | 2010-02-25 | — | — | US | disclosed |
| EP-1945711-A1 | FLAME RETARDANT COMPOSITION AND HYDROLYSIS-SUSCEPTIBLE RESIN CONTAINING SAME | Supresta LLC (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056456-A1 | FLAME RETARDANT COMPOSITION AND HYDROLYSIS-SUSCEPTIBLE RESIN CONTAINING SAME | SUPRESTA LLC (US) | 2007-05-18 | — | — | WO | disclosed |
| US-4102859-A | PHOSPHOROUS ACID ESTERS WITH OXETANE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
| US-3881030-A | 2,2-Diphenyl-3,3-dimethyloxetone insecticides | COMMW SCIENT IND RES ORG | 1975-04-29 | — | — | US | disclosed |