SCHEMBL34719

SCHEMBL34719

Cc1ccc(-c2nc3cc4[nH]c(C)nc4nc3[nH]2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 4/20 0.39
CBFB Q13951 4/20 0.39
METAP1 P53582 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
PKM P14618 1/20 0.39
POLB P06746 2/20 0.36
AURKA O14965 1/20 0.35
ABL1 P00519 2/20 0.35
KDR P35968 2/20 0.35
CDK7 P50613 2/20 0.35
CDK5 Q00535 2/20 0.35
AURKB Q96GD4 2/20 0.35
CLK4 Q9HAZ1 2/20 0.35
DYRK3 O43781 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35032 0.82 CBFB (0.50) METAP2CBFBMETAP1SMN1; SMN2NPC1
SCHEMBL13472250 0.82 METAP2 (0.56) METAP2CBFBMETAP1SMN1; SMN2NPC1
SCHEMBL35043 0.81 RAB9A (0.46) SMN1; SMN2NPC1RAB9APOLBAURKA
SCHEMBL13286926 0.78 METAP1 (0.49) METAP2CBFBMETAP1SMN1; SMN2NPC1
SCHEMBL35057 0.77 CCR1 (0.40) METAP2CBFBMETAP1SMN1; SMN2NPC1
SCHEMBL23786563 0.75 BRS3 (0.38) METAP2CBFBMETAP1NPC1RAB9A
SCHEMBL34724 0.75 NPBWR1 (0.49) SMN1; SMN2NPC1RAB9APKMPOLB
SCHEMBL35045 0.75 SMN1; SMN2 (0.37) SMN1; SMN2NPC1RAB9APOLBAURKA
SCHEMBL13533862 0.74 CCR1 (0.42) METAP2SMN1; SMN2NPC1RAB9ACCR1
SCHEMBL16257463 0.73 MEN1 (0.35) METAP2CBFBMETAP1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11799112-B2 Polybenzimidazole (PBI) membranes for redox flow batteries UNIVERSITY OF SOUTH CAROLINA (US) 2023-10-24 US disclosed
US-11777124-B2 Proton-conducting PBI membrane processing with enhanced performance and durability UNIVERSITY OF SOUTH CAROLINA (US) 2023-10-03 US disclosed
US-9997791-B2 Membrane electrode units for high temperature fuel cells with improved stability BASF SE (DE) 2018-06-12 US disclosed
US-20180123155-A1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2018-05-03 US disclosed
US-9825320-B2 Process for the manufacture of membrane electrode units BASF SE (DE) 2017-11-21 US disclosed
US-9812725-B2 Proton-conducting membrane and use thereof BASF SE (DE) 2017-11-07 US disclosed
US-9680156-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD (KR) 2017-06-13 US disclosed
EP-2804888-B1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2017-03-15 EP disclosed
US-9537166-B2 Method for the production of an electrochemical cell RENSSELAER POLYTECHNIC INSTITUTE (US) 2017-01-03 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-20070292734-A1 Polymer electrolyte membrane, method for the production thereof, and application thereof in fuel cells BASF FUEL CELL GMBH (DE) 2007-12-20 US disclosed
US-20070281204-A1 Membrane Electrode Assemblies and Highly Durable Fuel Cells PEMEAS GMBH (DE) 2007-12-06 US disclosed
US-20070248889-A1 Membrane Electrode Units and Fuel Cells with an Increased Service Life PEMEAS GMBH (DE) 2007-10-25 US disclosed
US-20070248863-A1 Membrane-Electrode Unit and Fuel Elements with Increased Service Life BASF FUEL CELL GMBH (DE) 2007-10-25 US disclosed
US-20070202415-A1 Proton-Conducting Polymer Membrane Comprising At Least One Porous Carrier Material, And Use Thereof In Fuel Cells PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-20070203252-A1 Anisotropic Shaped Bodies, Method For The Production And Utilization Of Anisotropic Shaped Bodies PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-7244811-B2 Method for the treatment of polyazole films PEMEAS GMBH (DE) 2007-07-17 US disclosed
US-20070151926-A1 HIGH-MOLECULAR-WEIGHT POLYAZOLES USED AS PROTON CONDUCTING MEMBRANES BASF FUEL CELL GMBH (DE) 2007-07-05 US disclosed
US-7235320-B2 Proton-conducting membrane and use thereof PEMEAS GMBH (DE) 2007-06-26 US disclosed
US-20070055045-A1 Proton-conducting polymer membrane containing polymers with sulfonic acid groups that are covalently bonded to aromatic groups, membrane electrode unit, and use thereof in fuel cells PEMEAS GMBH (DE) 2007-03-08 US disclosed