Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169224 | 0.85 | HTT (0.39) | HTTGRM1CYP1A2TDP1MEN1 | |
| SCHEMBL16744658 | 0.85 | HTT (0.39) | HTTGRM1CYP1A2TDP1MEN1 | |
| SCHEMBL1357313 | 0.85 | HTT (0.39) | HTTGRM1CYP1A2TDP1MEN1 | |
| SCHEMBL18839443 | 0.83 | DGAT1 (0.47) | EPHX1ALDH1A1PARP1DPP8DPP9 | |
| SCHEMBL6829540 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HTTKMT2AHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL29002530 | 0.79 | TSHR (0.40) | ALDH1A1HPGDKDM4ERXFP1 | |
| SCHEMBL9828746 | 0.77 | MAPT (0.36) | EPHX1PARP1GRM1CYP1A2TDP1 | |
| SCHEMBL31646465 | 0.77 | FLT1 (0.38) | EPHX1ALDH1A1PARP1GRM1CYP1A2 | |
| SCHEMBL2030601 | 0.76 | ALDH1A1 (0.44) | EPHX1ALDH1A1GAATDP1MEN1 | |
| SCHEMBL169457 | 0.75 | EPHX1 (0.33) | EPHX1HTTDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149360-A1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES | LONZA LTD (CH) | 2010-12-29 | — | — | WO | disclosed |