Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744658 | 1.00 | HTT (0.39) | HTTMEN1KMT2ACYP1A2GRM1 | |
| SCHEMBL8169224 | 1.00 | HTT (0.39) | HTTMEN1KMT2ACYP1A2GRM1 | |
| SCHEMBL3472223 | 0.85 | EPHX1 (0.36) | HTTMEN1KMT2ACYP1A2GRM1 | |
| SCHEMBL510474 | 0.83 | SRC (0.44) | MEN1KMT2ACYP1A2GRM1TDP1 | |
| SCHEMBL6829540 | 0.83 | ALDH1A1 (0.40) | HTTKMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2637191 | 0.82 | FPR2 (0.47) | AKR1C3AKR1C2AKR1C1PTGS1SMN1; SMN2 | |
| SCHEMBL2383322 | 0.82 | TSHR (0.40) | MEN1KMT2ATDP1AKR1C3AKR1C2 | |
| SCHEMBL3171360 | 0.80 | GRM1 (0.38) | MEN1KMT2ACYP1A2GRM1TDP1 | |
| SCHEMBL509516 | 0.80 | AKR1C3 (0.43) | MEN1KMT2ACYP1A2GRM1TDP1 | |
| SCHEMBL16747652 | 0.79 | ATM (0.40) | HTTKMT2ATDP1AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | AGXT, PAOX, DDT | HTT 1003/4885MEN1 3860/4885KMT2A 3415/4885 |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | DDT, EBP, TET1 | HTT 3700/4885MEN1 4824/4885KMT2A 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.