SCHEMBL3472344

SCHEMBL3472344

CO[Si](C)(C)C(C)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TRPA1 O75762 2/20 0.41
TDP1 Q9NUW8 1/20 0.38
HTR2A P28223 3/20 0.38
NFE2L2 Q16236 1/20 0.38
CYP1A2 P05177 2/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37
TUBA1C Q9BQE3 1/20 0.37
TUBB6 Q9BUF5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3472250 0.85 MEN1 (0.42) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL80330 0.83 TRPA1 (0.42) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL80331 0.83 TRPA1 (0.42) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL16912873 0.81 MEN1 (0.42) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL16912875 0.81 MEN1 (0.42) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL3478256 0.78 MEN1 (0.43) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL3478255 0.78 MEN1 (0.43) MEN1KMT2ATRPA1TDP1HTR2A
SCHEMBL16912872 0.77 MEN1 (0.41) MEN1KMT2AHTR2ACYP1A2MAOB
SCHEMBL8600084 0.77 MEN1 (0.41) MEN1KMT2AHTR2ACYP1A2MAOB
SCHEMBL2144291 0.77 MEN1 (0.41) MEN1KMT2AHTR2ACYP1A2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
US-20190056360-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2019-02-21 US claimed
US-10119944-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2018-11-06 US claimed
US-20150204824-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2015-07-23 US claimed
US-7842498-B2 Hydrophobic surface chip BIO-RAD LABORATORIES, INC. (US) 2010-11-30 US claimed
US-7517496-B2 Latex based adsorbent chip BIO-RAD LABORATORIES, INC. (US) 2009-04-14 US claimed
JP-4150673-B2 2008-09-17 JP claimed
EP-1483794-A4 LATEX BASED ADSORBENT CHIP CIPHERGEN BIOSYSTEMS INC (US) 2006-05-03 EP claimed
JP-2005509155-A 2005-04-07 JP claimed
EP-1451554-A4 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS INC (US) 2004-12-15 EP claimed
EP-1483794-A2 LATEX BASED ADSORBENT CHIP Ciphergen Biosystems, Inc. (US) 2004-12-08 EP claimed
EP-1451554-A1 HYDROPHOBIC SURFACE CHIP Ciphergen Biosystems, Inc. (US) 2004-09-01 EP claimed
WO-2003079402-A2 LATEX BASED ADSORBENT CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-09-25 WO claimed
US-20030124371-A1 Hydrophobic surface chip CIPHERGEN BIOSYSTEMS, INC. 2003-07-03 US claimed
WO-2003040700-A1 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-05-15 WO claimed
US-20030032043-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-02-13 US claimed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US claimed
US-12365751-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2025-07-22 US disclosed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US disclosed