SCHEMBL80330

SCHEMBL80330

CO[Si](OC)(OC)C(C)/C=C/c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
HTR2A P28223 3/20 0.39
NFE2L2 Q16236 1/20 0.39
MAOB P27338 1/20 0.38
CYP1A2 P05177 2/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80331 1.00 TRPA1 (0.42) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL1408631 0.92 TRPA1 (0.37) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL1408632 0.92 TRPA1 (0.37) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL5924268 0.88 NFE2L2 (0.49) TRPA1NFE2L2CYP1A2TUBB4ATUBB
SCHEMBL3472250 0.83 MEN1 (0.42) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL3472344 0.83 MEN1 (0.42) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL3734443 0.81 MEN1 (0.41) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL3734441 0.81 MEN1 (0.41) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL1572472 0.80 RELA (0.43) TRPA1MEN1KMT2ATDP1HTR2A
SCHEMBL1572470 0.80 RELA (0.43) TRPA1MEN1KMT2ATDP1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1653 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
EP-4619470-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME Synthomer Sdn. Bhd. (MY) 2025-09-24 EP claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
EP-4553121-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI Advanced Materials Co., Ltd. (KR) 2025-05-14 EP claimed
CN-119661782-A PVDF material with dispersed anti-gel function for positive electrode slurry and preparation method thereof 郑州大学 2025-03-21 CN claimed
US-20030032043-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-02-13 US claimed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US claimed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO claimed
WO-2000064969-A9 NANOCOMPOSITE OF POLYMERIC MATERIALS WITH SURFACE MODIFIED CLAY AND SILICA XEROGEL IND SCIENCE & TECHNOLOGY NETWO (US) 2002-02-21 WO claimed
WO-2000064969-A1 NANOCOMPOSITE OF POLYMERIC MATERIALS WITH SURFACE MODIFIED CLAY AND SILICA XEROGEL INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC. (US) 2000-11-02 WO claimed
US-6136874-A Microporous polymeric foams made with silicon or germanium based monomers THE PROCTER & GAMBLE COMPANY (US) 2000-10-24 US claimed
US-6090491-A MEMBER HAVING IMPROVED TONER OFFSET RELEASE AND WEAR CHARACTERISTICS EASTMAN KODAK COMPANY (US) 2000-07-18 US claimed
US-5868966-A IONIC POLYMER, E.G. DOPED POLYANILINE, AN UNSATURATED COMPOUND HAVING A REACTIVE PENDANT GROUP, E.G 3-TRIMETHYOXYSILYLPROPYL METHACRYLATE, AND A ?GLASS? COMPONENT, E.G TETRAETHYLSILICATE; ADHESION; PROTECTIVE COATINGS DREXEL UNIVERSITY (US) 1999-02-09 US claimed
EP-0268243-B1 Packing material and process for its production TOSOH CORP (JP) 1997-08-13 EP claimed
EP-0268243-A2 Packing material and process for its production Tosoh Corporation (JP) 1988-05-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629657-B2 Lithium ion adsorbents ILK, SDC1, LAMTOR3 TRPA1 3137/4885MEN1 1367/4885KMT2A 1571/4885
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL TRPA1 878/4885MEN1 2740/4885KMT2A 31/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA TRPA1 1843/4885MEN1 3136/4885KMT2A 4509/4885
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME AOC1, AOC2, DDT TRPA1 1191/4885MEN1 1343/4885KMT2A 330/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 TRPA1 1109/4885MEN1 2266/4885KMT2A 979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.