Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911622 | 0.83 | MEN1 (0.53) | ALDH1A1HPGDTSHRSMN1; SMN2KDM4E | |
| SCHEMBL1911623 | 0.83 | MEN1 (0.53) | ALDH1A1HPGDTSHRSMN1; SMN2KDM4E | |
| SCHEMBL348399 | 0.72 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL4023755 | 0.71 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL4025720 | 0.69 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28801191 | 0.69 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL13787617 | 0.68 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL16432263 | 0.68 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL347469 | 0.67 | SCD (0.54) | ALDH1A1HPGDKMT2APOLBSCD | |
| SCHEMBL16404868 | 0.67 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318949-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-11-27 | — | — | US | disclosed |
| US-20120014906-A1 | ORGANIC COMPOUNDS | XENON PHARMACEUTICALS INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8049016-B2 | Thiazole derivatives which inhibit stearoyl-CoA desaturase enzymes | NOVARTIS AG (CH) | 2011-11-01 | — | — | US | disclosed |
| US-20090264444-A1 | Organic compounds | XENON PHARMACEUTICALS INC. (CA) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014906-A1 | ORGANIC COMPOUNDS | SCD, SCD5, FADS2 | PIK3CD 2361/4885PIK3CA 2130/4885PIK3CB 1909/4885 |
| US-20090264444-A1 | Organic compounds | SCD, SCD5, FADS2 | PIK3CD 2361/4885PIK3CA 2130/4885PIK3CB 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.