SCHEMBL3472672

SCHEMBL3472672

CC(=O)Oc1ccc(COS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
PKM P14618 1/20 0.53
ALDH1A1 P00352 2/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
KMT2A Q03164 3/20 0.47
MAOB P27338 1/20 0.46
EGFR P00533 1/20 0.42
PARP10 Q53GL7 1/20 0.41
STAT3 P40763 1/20 0.41
MEN1 O00255 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
ENPP1 P22413 1/20 0.41
GAA P10253 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738988 0.87 CA1 (0.43) LMNAPOLBMAPTPKMALDH1A1
SCHEMBL8052920 0.84 CA2 (0.63) MAPTALDH1A1CA1CA2CA9
SCHEMBL6859827 0.84 CA2 (0.63) MAPTALDH1A1CA1CA2CA9
SCHEMBL13172297 0.83 ELANE (0.47) LMNAMAPTALDH1A1CA1CA2
SCHEMBL5870597 0.82 ALDH1A1 (0.57) LMNAPKMALDH1A1CA1CA2
SCHEMBL7890851 0.82 CA2 (0.56) LMNAPOLBMAPTALDH1A1CA1
SCHEMBL2539991 0.81 LMNA (0.54) LMNAPOLBMAPTPKMALDH1A1
SCHEMBL25138830 0.80 LMNA (0.67) LMNAPOLBMAPTPKMALDH1A1
SCHEMBL19067740 0.80 CA2 (0.54) LMNAMAPTALDH1A1CA1CA2
SCHEMBL27207780 0.80 LMNA (0.67) LMNAPOLBMAPTPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838602-B2 Weatherable, thermostable polymers having improved flow composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-11-23 US disclosed
US-7605221-B2 Aromatic polycarbonateester block or random copolymer and polysiloxane blend primarily containing isophthalic and terephthalic acids, resorcinol and dimethylsilanediol monomers; films are radiation transparent; improved ductility at lower temperatures; aircraft components SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US disclosed
EP-2032624-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 EP disclosed
US-7432327-B2 Transparent polymeric compositions comprising polysiloxane-polycarbonate copolymer, articles made therefrom and methods of making same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-07 US disclosed
US-7321014-B2 Transparent compositions, methods for the preparation thereof, and articles derived therefrom GENERAL ELECTRIC COMPANY (US) 2008-01-22 US disclosed
WO-2008002757-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 WO disclosed
EP-1833873-A2 TRANSPARENT COMPOSITIONS, METHODS FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM General Electric Company (US) 2007-09-19 EP disclosed
EP-1833919-A1 TRANSPARENT POLYMERIC COMPOSITIONS COMPRISING POLYSILOXANE-POLYCARBONATE COPOLYMER, ARTICLES MADE THEREFROM AND METHODS OF MAKING SAME General Electric Company (US) 2007-09-19 EP disclosed
US-20070122627-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-05-31 US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 US disclosed
WO-2006073901-A1 TRANSPARENT POLYMERIC COMPOSITIONS COMPRISING POLYSILOXANE-POLYCARBONATE COPOLYMER, ARTICLES MADE THEREFROM AND METHODS OF MAKING SAME GENERAL ELECTRIC COMPANY (US) 2006-07-13 WO disclosed
WO-2006071682-A2 TRANSPARENT COMPOSITIONS, METHODS FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2006-07-06 WO disclosed
US-20060148986-A1 Transparent polymeric compositions comprising polysiloxane-polycarbonate copolymer, articles made therefrom and methods of making same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-07-06 US disclosed
US-20060142527-A1 Transparent compositions, methods for the preparation thereof, and articles derived therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-06-29 US disclosed
US-20050159577-A1 Weatherable, thermostable polymers having improved flow composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-07-21 US disclosed