Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | WRN | Q14191 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467926 | 0.81 | SCD (0.51) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3467988 | 0.80 | SMN1; SMN2 (0.69) | LMNAMAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL20887245 | 0.74 | SMN1; SMN2 (0.61) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5445001 | 0.71 | BLM (0.61) | LMNAMAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL3467629 | 0.70 | L3MBTL1 (0.71) | L3MBTL1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3467628 | 0.70 | GLS (0.50) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5448580 | 0.70 | HTT (0.72) | LMNAMAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL3467090 | 0.70 | MEN1 (0.68) | LMNAMAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL32672104 | 0.70 | POLB (0.59) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5446203 | 0.69 | KMT2A (0.56) | MAPTL3MBTL1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |