Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468581 | 0.82 | TP53 (0.65) | SMN1; SMN2LMNAMAPTL3MBTL1POLB | |
| SCHEMBL20887240 | 0.81 | KDM4E (0.79) | SMN1; SMN2LMNAMAPTL3MBTL1POLB | |
| SCHEMBL3472807 | 0.80 | LMNA (0.54) | SMN1; SMN2LMNAMAPTL3MBTL1POLB | |
| SCHEMBL3467104 | 0.80 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1POLBALDH1A1MEN1 | |
| SCHEMBL12793509 | 0.80 | MEN1 (0.76) | SMN1; SMN2LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL12838825 | 0.77 | ALDH1A1 (0.72) | SMN1; SMN2LMNAMAPTL3MBTL1POLB | |
| SCHEMBL29047587 | 0.76 | L3MBTL1 (0.60) | SMN1; SMN2L3MBTL1POLBALDH1A1MEN1 | |
| SCHEMBL32672104 | 0.76 | POLB (0.59) | SMN1; SMN2LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL3467629 | 0.74 | L3MBTL1 (0.71) | SMN1; SMN2L3MBTL1POLBALDH1A1MEN1 | |
| SCHEMBL3467628 | 0.74 | GLS (0.50) | SMN1; SMN2LMNAMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |