Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473510 | 0.97 | CHEK1 (0.46) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3472148 | 0.81 | CHEK1 (0.54) | CHEK1PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL38652511 | 0.76 | PARP1 (0.50) | CHEK1PNPPARP1KDM4EALDH1A1 | |
| SCHEMBL31322401 | 0.76 | KDM4E (0.55) | CHEK1PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL17396507 | 0.76 | RXFP1 (0.55) | CHEK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6826519 | 0.75 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL6826816 | 0.75 | KDM4E (0.58) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL31322412 | 0.72 | PARP1 (0.54) | PARP1KDM4EHSD17B10CDK4CCND1 | |
| SCHEMBL25619045 | 0.71 | KDM4E (0.60) | CHEK1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL3473512 | 0.71 | PARP1 (0.45) | CHEK1PARP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193430-B2 | Methods for separating carbon nanotubes | THE UNIVERSITY OF CONNECTICUT (US) | 2012-06-05 | — | — | US | disclosed |
| US-20100044230-A1 | METHODS FOR SEPARATING CARBON NANOTUBES | UNIVERSITY OF CONNECTICUT (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044230-A1 | METHODS FOR SEPARATING CARBON NANOTUBES | FSCN1, TTPA, FLNB | CHEK1 2918/4885GRIN2D 3798/4885GRIN3B 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.