Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326515 | 0.72 | DGAT1 (0.44) | DGAT1CA1CA2CA7 | |
| SCHEMBL7473418 | 0.69 | DGAT1 (0.35) | DGAT1CA1CA2 | |
| SCHEMBL161854 | 0.68 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL11552854 | 0.68 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL14606262 | 0.68 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL15965830 | 0.66 | DGAT1 (0.48) | DGAT1CA1CA2CA7 | |
| SCHEMBL13206619 | 0.66 | DGAT1 (0.48) | DGAT1CA1CA2CA7 | |
| SCHEMBL12199750 | 0.66 | DGAT1 (0.48) | DGAT1CA1CA2CA7 | |
| SCHEMBL21058313 | 0.64 | DGAT1 (0.46) | DGAT1CA1CA2 | |
| SCHEMBL22962550 | 0.64 | DGAT1 (0.46) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318960-B2 | Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2012-11-27 | — | — | US | disclosed |
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | MVD, DDT, AGPS | DGAT1 2291/4885CA1 1821/4885CA2 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.