SCHEMBL3473759

SCHEMBL3473759

O=P(Oc1cccc2ccccc12)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HSD17B10 Q99714 2/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MITF O75030 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
KCNA3 P22001 1/20 0.42
OGG1 O15527 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
PGR P06401 1/20 0.41
GAA P10253 1/20 0.41
PTGS1 P23219 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464630 0.85 L3MBTL1 (0.52) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL30912783 0.82 MAPT (0.50) ALDH1A1TDP1HSD17B10L3MBTL1MEN1
SCHEMBL31506303 0.82 ALDH1A1 (0.47) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL30544121 0.82 ALDH1A1 (0.50) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL29613147 0.80 HTT (0.53) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL263618 0.80 HTT (0.53) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL25260285 0.80 TDP1 (0.65) HTTALDH1A1KDM4EHPGDTDP1
SCHEMBL9973243 0.80 CYP1A2 (0.40) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL29035773 0.79 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDL3MBTL1MEN1
SCHEMBL17333428 0.79 HTT (0.51) HTTALDH1A1KDM4EHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645851-B2 Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-12 US claimed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP claimed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO claimed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US claimed
CN-107082789-B Method for preparing organic phosphate compound by efficiently esterifying P (O) -OH-containing compound and phenol 湖南理工学院 2020-08-28 CN disclosed
US-8962788-B2 Production of a polycarbonate with limited metal residuals SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-02-24 US disclosed
WO-2014141108-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 WO disclosed
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-09-18 US disclosed
EP-2041202-B1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP (NL) 2013-05-08 EP disclosed
US-7645851-B2 Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-12 US disclosed
US-7541420-B2 Method for making molded polycarbonate articles with improved color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-02 US disclosed
EP-2041202-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-04-01 EP disclosed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP disclosed
WO-2008005633-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed
US-20080004407-A1 Molding polycarbonate resin made by a transesterification reaction using an activated diaryl carbonate such that the polycarbonate is susceptible to formation of internal ester linkages (IEL), and controlling (IEL) through incorporation of phosphite additive that inhibits the linkages GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS BMI1, EZH2, SUV39H2 HTT 3870/4885ALDH1A1 4642/4885KDM4E 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.