Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475812 | 0.87 | FAAH (0.62) | FAAHHDAC6PIK3CA | |
| SCHEMBL3477409 | 0.83 | FAAH (0.71) | FAAHHDAC6PIK3CAALDH1A1ELANE | |
| SCHEMBL3477307 | 0.81 | FAAH (0.66) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3476716 | 0.81 | FAAH (0.63) | FAAHHDAC6PIK3CA | |
| SCHEMBL3475819 | 0.80 | FAAH (0.65) | FAAHHDAC6PIK3CAALDH1A1ELANE | |
| SCHEMBL3477717 | 0.78 | HDAC6 (0.67) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477428 | 0.77 | FAAH (0.64) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL13436763 | 0.77 | FAAH (0.76) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477494 | 0.76 | FAAH (0.60) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3476787 | 0.76 | FAAH (0.72) | FAAHHDAC6PIK3CAALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |