Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476876 | 0.86 | FAAH (0.77) | FAAHHDAC6PIK3CARPS6KA2SSTR5 | |
| SCHEMBL3474867 | 0.85 | FAAH (0.69) | FAAHHDAC6PIK3CARPS6KA2ELANE | |
| SCHEMBL3476698 | 0.84 | FAAH (1.00) | FAAHHDAC6PIK3CARPS6KA2ELANE | |
| SCHEMBL3476655 | 0.84 | FAAH (0.69) | FAAHHDAC6PIK3CARPS6KA2ELANE | |
| SCHEMBL13436724 | 0.84 | FAAH (0.63) | FAAHHDAC6PIK3CARPS6KA2HTR6 | |
| SCHEMBL3477435 | 0.83 | FAAH (0.75) | FAAHHDAC6PIK3CAALDH1A1HPGD | |
| SCHEMBL3475486 | 0.83 | FAAH (0.69) | FAAHHDAC6PIK3CARPS6KA2SSTR5 | |
| SCHEMBL13436720 | 0.83 | FAAH (0.78) | FAAHHDAC6PIK3CASMN1; SMN2RPS6KA2 | |
| SCHEMBL3477409 | 0.83 | FAAH (0.71) | FAAHHDAC6PIK3CAALDH1A1TP53 | |
| SCHEMBL3476255 | 0.83 | FAAH (0.62) | FAAHHDAC6PIK3CARPS6KA2SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |