Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670085 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1KDM4EPKM | |
| SCHEMBL10670562 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1KDM4EPKM | |
| SCHEMBL6736271 | 0.83 | CYP1A2 (0.60) | SMN1; SMN2ALDH1A1TDP1HPGDL3MBTL1 | |
| SCHEMBL18612334 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1KDM4EPKM | |
| SCHEMBL6001878 | 0.81 | PTGS1 (0.51) | SMN1; SMN2ALDH1A1TDP1HPGDL3MBTL1 | |
| SCHEMBL20733630 | 0.79 | PTGS1 (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL13283703 | 0.79 | PTGS1 (0.50) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11218369 | 0.79 | ALOX15 (0.47) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9706284 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ANPC1KDM4EPKM | |
| SCHEMBL8139010 | 0.79 | PPARG (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| CN-110423210-A | A kind of benzyl aryl thioethers derivative and its preparation method and application | UNIV JINAN | 2019-11-08 | — | — | CN | claimed |
| CN-108239044-A | The synthetic method of aftereffect accelerant N-cyclohexyl -2-[4-morpholinodithio sulfenamide | 成都卡迪夫科技有限公司 | 2018-07-03 | — | — | CN | claimed |
| CN-108187824-A | Compression set and its method of work are crushed for underground sewage harnessing project rotating disc type | 徐州工程学院 | 2018-06-22 | — | — | CN | claimed |
| CN-102731432-B | The fluorination process of anilid derivative and the benzothiazole fluorinated derivatives as in-vivo imaging agent | GE HEALTHCARE LTD. (GB) | 2015-10-21 | — | — | CN | claimed |
| EP-2271650-B1 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | claimed |
| EP-2493893-B1 | AZABICYCLO[2.2.1]HEPTANE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2014-01-15 | — | — | EP | claimed |
| EP-2111483-A1 | CORROSION INHIBITOR | Ascotec (FR) | 2009-10-28 | — | — | EP | claimed |
| WO-2008107529-A1 | CORROSION INHIBITOR | ASCOTEC (FR) | 2008-09-12 | — | — | WO | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| US-5409835-A | Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion concentrations | THE UNIVERSITY OF MARYLAND AT BALTIMORE (US) | 1995-04-25 | — | — | US | claimed |
| JP-1272565-A | — | — | None | — | — | JP | disclosed |
| JP-55011532-A | — | — | None | — | — | JP | disclosed |
| JP-55002643-A | — | — | None | — | — | JP | disclosed |
| JP-55002642-A | — | — | None | — | — | JP | disclosed |
| EP-0024525-A1 | Process for the preparation of luciferin and its derivatives | Roche Diagnostics GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| JP-S5511532-A | PREPARATION OF N-METHYL-BENZTHIAZOLONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1980-01-26 | — | — | JP | disclosed |
| JP-S552643-A | PREPARATION OF N-METHYL-BENZTHIAZOLONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1980-01-10 | — | — | JP | disclosed |
| JP-S552642-A | PREPARATION OF N-METHYL-BENZTHIAZOLONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1980-01-10 | — | — | JP | disclosed |
| US-3994733-A | CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE | FUJI PHOTO FILM CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |