SCHEMBL6736271

SCHEMBL6736271

c1ccc2sc(Oc3nc4ccccc4s3)nc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.60
CYP2D6 P10635 3/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C19 P33261 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
PTGS1 P23219 4/20 0.53
PTGS2 P35354 4/20 0.53
ALDH1A1 P00352 1/20 0.52
ADRA2A P08913 1/20 0.52
FBP1 P09467 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
DRD2 P14416 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ADRA2B P18089 1/20 0.52
ADRA2C P18825 1/20 0.52
DRD1 P21728 1/20 0.52
MC5R P33032 1/20 0.52
OPRM1 P35372 1/20 0.52
DRD3 P35462 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11471037 0.90 CYP1A2 (0.73) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL357361 0.88 SMN1; SMN2 (0.71) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL6001878 0.84 PTGS1 (0.51) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL6361195 0.83 SMN1; SMN2 (0.50) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL13283703 0.83 PTGS1 (0.50) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL20733630 0.83 PTGS1 (0.54) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL347497 0.83 SMN1; SMN2 (0.54) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL18612334 0.82 SMN1; SMN2 (0.64) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL10767866 0.82 MAPT (0.57) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2
SCHEMBL17580987 0.82 CYP1A2 (0.49) CYP1A2CYP2D6CYP3A4CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383859-A Imidazo benzothiazole ether compound and its officinal salt preparation method and application 西南大学 2018-08-10 CN claimed
CN-108383859-A Imidazo benzothiazole ether compound and its officinal salt preparation method and application 西南大学 2018-08-10 CN disclosed
CN-108383859-A Imidazo benzothiazole ether compound and its officinal salt preparation method and application 西南大学 2018-08-10 CN disclosed
CN-108383859-A Imidazo benzothiazole ether compound and its officinal salt preparation method and application 西南大学 2018-08-10 CN disclosed
US-20160003995-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-01-07 US disclosed
CN-101697737-B Bacillus subtilis and tricyclazole compound wettable sterilizing powder and application thereof JIANGSU ACAD AGRICULTURAL SCI 2012-04-25 CN disclosed
CN-102076655-A Insecticidal compounds SYNGENTA PARTICIPATIONS AG 2011-05-25 CN disclosed
CN-101960062-A Be used to improve the fabric structure of ballisticimpact performance DU PONT 2011-01-26 CN disclosed
CN-101697737-A Bacillus subtilis and compound wettable sterilizing powder and use thereof JIANGSU ACAD AGRICULTURAL SCI 2010-04-28 CN disclosed
CN-1329752-C K-type polarizer and preparation thereof 3M INNOVATIVE PROPERTIES CO (US) 2007-08-01 CN disclosed
US-20040116297-A1 Use of polyprenol and its derivatives for facilitating growth of plants KWON SEONG-RYONG (KR) 2004-06-17 US disclosed
EP-1243043-A1 HIGH TEMPERATURE POLYBENZAZOLE AND POLYETHER ELECTROLYTES Sri International (US) 2002-09-25 EP disclosed
US-6176984-B1 HIGH TEMPERATURE POLYBENZAZOLE POLYMER ELECTROLYTE COMPRISES A BENZOBISOXAZOLE, A BENZOBISTHIAZOLE OR A BENZOBISIMIDAZOLE HOMO OR COPOLYMERS SRI INTERNATIONAL 2001-01-23 US disclosed
WO-2001001506-A1 HIGH TEMPERATURE POLYBENZAZOLE AND POLYETHER ELECTROLYTES SRI INTERNATIONAL (US) 2001-01-04 WO disclosed
CN-1153926-A Oximesulfonic acid esters and use thereof as latent sulfonic acids CIBA GEIGY AG (CH) 1997-07-09 CN disclosed
US-5077046-A Plant extracts; mannaliam dolichols intermediates KURARAY CO., LTD. (JP) 1991-12-31 US disclosed
US-5012018-A Extending polyisoprene chain using copper catalyst KURARAY CO., LTD. (JP) 1991-04-30 US disclosed
US-4886904-A CONTAINING CIS AND TRANS ISOPRENE UNITS KURARAY CO., LTD. (JP) 1989-12-12 US disclosed
EP-0054753-B1 POLYPRENYL COMPOSITION OR COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF KURARAY CO., LTD. (JP) 1985-07-24 EP disclosed
EP-0054753-A1 Polyprenyl composition or compounds and process for the production thereof KURARAY CO., LTD. (JP) 1982-06-30 EP disclosed