Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736271 | 0.84 | CYP1A2 (0.60) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL13283703 | 0.81 | PTGS1 (0.50) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL20733630 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL347497 | 0.81 | SMN1; SMN2 (0.54) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL10670562 | 0.79 | SMN1; SMN2 (0.53) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL729697 | 0.79 | PTGS1 (0.51) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL10670085 | 0.79 | SMN1; SMN2 (0.53) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11471037 | 0.79 | CYP1A2 (0.73) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL8667042 | 0.78 | CYP1A2 (0.50) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL357361 | 0.78 | SMN1; SMN2 (0.71) | PTGS1PTGS2CYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| JP-1272565-A | — | — | None | — | — | JP | disclosed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |
| CN-1279818-C | Herbicidal synergistic composition, and method of controlling weeds | SYNGENTA CROP PROT INC (CH) | 2006-10-18 | — | — | CN | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| CN-1541532-A | Herbicidal synergistic composition, and method of controlling weeds | �����ɷ� | 2004-11-03 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0768034-A1 | Synergistic herbicidal composition and method for weed control | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |
| JP-H01272565-A | N-BENZENESULFONYLAMIDINE DERIVATIVE AND PESTICIDE FOR RICE BLAST CONTAINING THE SAME DERIVATIVE AS ACTIVE COMPONENT | SHIONOGI & CO LTD | 1989-10-31 | — | — | JP | disclosed |