Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22219086 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4ETDP1RECQL | |
| SCHEMBL8420025 | 0.94 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4ETDP1HPGD | |
| SCHEMBL16515501 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4EHPGDL3MBTL1 | |
| SCHEMBL3631558 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ETDP1HPGD | |
| SCHEMBL4364410 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4ETDP1RECQLL3MBTL1 | |
| SCHEMBL22219023 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1LMNAKDM4ETDP1RECQL | |
| SCHEMBL13021583 | 0.79 | MEN1 (0.45) | ALDH1A1LMNAKDM4ETDP1RECQL | |
| SCHEMBL13413138 | 0.79 | KDM4E (0.42) | ALDH1A1LMNAKDM4ETDP1RECQL | |
| SCHEMBL8251597 | 0.78 | GPR84 (0.42) | LMNAKDM4ETDP1RECQLHPGD | |
| SCHEMBL15430841 | 0.78 | HPGD (0.51) | ALDH1A1KDM4ETDP1RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141758-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141758-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141754-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141754-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NAT1, AADAC, CORO1C | ALDH1A1 27/4885LMNA 2010/4885KDM4E 3318/4885 |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | B3GNT2, GSTO1, NAT1 | ALDH1A1 15/4885LMNA 4201/4885KDM4E 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.