SCHEMBL347544

SCHEMBL347544

NC(=O)c1cc2ccccc2s1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.69
SLC9A1 P19634 2/20 0.67
HDAC3 O15379 1/20 0.65
HDAC4 P56524 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC7 Q8WUI4 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC10 Q969S8 1/20 0.65
HDAC11 Q96DB2 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
HDAC9 Q9UKV0 1/20 0.65
HDAC5 Q9UQL6 1/20 0.65
DYRK1A Q13627 2/20 0.59
CHEK1 O14757 1/20 0.59
AURKA O14965 1/20 0.59
DAPK3 O43293 1/20 0.59
PRKD3 O94806 1/20 0.59
MAP4K4 O95819 1/20 0.59
PAK4 O96013 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366392 1.00 BCL2L1 (0.69) BCL2L1SLC9A1HDAC3HDAC4HDAC1
Hydrochloric Acid SCHEMBL2196804 0.98 BCL2L1 (0.67) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL28162040 0.85 DYRK1A (0.51) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL8958420 0.85 BCL2L1 (0.65) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL31356465 0.83 BCL2L1 (0.74) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL7209477 0.83 BCL2L1 (0.74) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL6321234 0.83 BCL2L1 (0.74) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL28162038 0.83 DYRK1A (0.50) BCL2L1SLC9A1HDAC3HDAC4HDAC1
Tetrazole SCHEMBL6927480 0.82 SLC9A1 (0.49) BCL2L1SLC9A1HDAC3HDAC4HDAC1
SCHEMBL4070224 0.82 BCL2L1 (0.61) BCL2L1SLC9A1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704828-A2 INHIBITORS OF JUN N-TERMINAL KINASES (JNK1, JNK2, AND/OR JNK3) AND MITOGEN-ACTIVATED PROTEIN KINASES (MAPK8, MAPK9, AND/OR MAPK10) AND METHODS OF USING SAME Baylor College of Medicine (US) 2026-03-11 EP claimed
US-12391680-B2 Compounds and compositions for the treatment of cystic fibrosis FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-08-19 US claimed
WO-2024226609-A2 INHIBITORS OF JUN N-TERMINAL KINASES (JNK1, JNK2, AND/OR JNK3) AND MITOGEN-ACTIVATED PROTEIN KINASES (MAPK8, MAPK9, AND/OR MAPK10) AND METHODS OF USING SAME BAYLOR COLLEGE OF MEDICINE (US) 2024-10-31 WO claimed
US-12005253-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2024-06-11 US claimed
EP-4363043-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2024-05-08 EP claimed
EP-4365181-A1 GALACTOSIDE DERIVATIVE AS GALECTIN-3 INHIBITOR TiumBio Co., Ltd. (KR) 2024-05-08 EP claimed
CN-117836306-A Galactose glycoside derivatives as galectin-3 inhibitors 株式会社蒂奥姆生物 2024-04-05 CN claimed
CN-114836201-B Zinc ion-mediated fluorescence sensor and preparation method and application thereof 哈尔滨理工大学 2024-01-26 CN claimed
WO-2023275649-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2023-01-05 WO claimed
US-20230001193-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS BIOPHARMA CREDIT PLC (GB) 2023-01-05 US claimed
US-5712304-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-27 US claimed
CN-1157617-A Heterobicyclic derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1997-08-20 CN claimed
EP-0770079-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-02 EP claimed
EP-0512349-B1 Benzothiophene-2-carboxamide-S,S-dioxides BAYER AG (DE) 1996-02-14 EP claimed
WO-1996001825-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-01-25 WO claimed
EP-0649649-A2 Colloidal, dispersible formulations of active substances BAYER AG (DE) 1995-04-26 EP claimed
US-5244893-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-09-14 US claimed
EP-0512349-A1 Benzothiophene-2-carboxamide-S,S-dioxides BAYER AG (DE) 1992-11-11 EP claimed
US-4761424-A Enolamides, pharmaceutical compositions and methods for treating inflammation WARNER-LAMBERT COMPANY (US) 1988-08-02 US claimed
EP-0221345-A1 Novel enolamides, process for their manufacture and pharmaceutical compositions thereof with an activity as modulators of the arachidonic acid cascade WARNER-LAMBERT COMPANY (US) 1987-05-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391680-B2 Compounds and compositions for the treatment of cystic fibrosis CFTR, ABCB11, ABCC5 BCL2L1 2334/4885SLC9A1 91/4885HDAC3 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.