Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625846 | 0.80 | NPC1 (0.61) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL5281489 | 0.79 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL25912039 | 0.78 | RAPGEF4 (0.58) | MAPTSMN1; SMN2TP53HPGDGAA | |
| SCHEMBL21625849 | 0.78 | NPC1 (0.44) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL8386481 | 0.77 | NPC1 (0.57) | MAPK14MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL21625850 | 0.77 | RAPGEF4 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4607773 | 0.75 | MAPT (0.86) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL3476199 | 0.75 | EGFR (0.52) | MAPK14MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8330820 | 0.74 | RAPGEF4 (0.49) | SMN1; SMN2TP53GAAMEN1KMT2A | |
| SCHEMBL29609435 | 0.74 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968955-B1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORP (US) | 2013-02-06 | — | — | EP | claimed |
| US-7704929-B2 | Diaromatic amine derivatives as antioxidants | CHEMTURA CORPORATION (US) | 2010-04-27 | — | — | US | claimed |
| EP-1968955-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2008-09-17 | — | — | EP | claimed |
| WO-2007081479-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2007-07-19 | — | — | WO | claimed |
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | LANXESS SOLUTIONS US INC. | 2007-07-05 | — | — | US | claimed |
| EP-1968955-B1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORP (US) | 2013-02-06 | — | — | EP | disclosed |
| US-7704929-B2 | Diaromatic amine derivatives as antioxidants | CHEMTURA CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| EP-1968955-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007081479-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | LANXESS SOLUTIONS US INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | C9, C5, C1S | MAPK14 2457/4885MAPK13 2753/4885MAPK12 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.