Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912039 | 0.88 | RAPGEF4 (0.58) | EGFRADRA2AADRA2BADRA2CRAPGEF4 | |
| SCHEMBL379238 | 0.83 | RAPGEF4 (0.63) | EGFRADRA2AADRA2BADRA2CRAPGEF4 | |
| SCHEMBL8386481 | 0.82 | NPC1 (0.57) | MAPK14ADRA2AADRA2BADRA2CRAPGEF4 | |
| SCHEMBL8634550 | 0.81 | RAPGEF4 (0.62) | ADRA2AADRA2BADRA2CRAPGEF4ALDH1A1 | |
| SCHEMBL18583900 | 0.79 | RAPGEF4 (0.52) | EGFRMAPK14ADRA2AADRA2BADRA2C | |
| SCHEMBL12377130 | 0.78 | NPC1 (0.62) | MAPK14ADRA2AADRA2BADRA2CRAPGEF4 | |
| SCHEMBL1673420 | 0.77 | RAPGEF4 (0.67) | ADRA2AADRA2BADRA2CRAPGEF4ALDH1A1 | |
| SCHEMBL15152202 | 0.77 | RAPGEF4 (0.53) | MAPK14ADRA2AADRA2BADRA2CRAPGEF4 | |
| SCHEMBL264473 | 0.77 | ADRA2A (0.47) | EGFRADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8810023 | 0.76 | CYP26A1 (0.53) | EGFRADRA2AADRA2BADRA2CRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968955-B1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORP (US) | 2013-02-06 | — | — | EP | claimed |
| US-7704929-B2 | Diaromatic amine derivatives as antioxidants | CHEMTURA CORPORATION (US) | 2010-04-27 | — | — | US | claimed |
| EP-1968955-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2008-09-17 | — | — | EP | claimed |
| WO-2007081479-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2007-07-19 | — | — | WO | claimed |
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | LANXESS SOLUTIONS US INC. | 2007-07-05 | — | — | US | claimed |
| EP-1968955-B1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORP (US) | 2013-02-06 | — | — | EP | disclosed |
| US-7704929-B2 | Diaromatic amine derivatives as antioxidants | CHEMTURA CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| EP-1968955-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007081479-A1 | DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS | CHEMTURA CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | LANXESS SOLUTIONS US INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155633-A1 | Diaromatic amine derivatives as antioxidants | C9, C5, C1S | EGFR 2578/4885MAPK14 2457/4885ADRA2A 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.