Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476787 | 0.83 | FAAH (0.72) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL3477409 | 0.83 | FAAH (0.71) | FAAHPIK3CAHDAC6AAK1 | |
| SCHEMBL3477293 | 0.83 | FAAH (0.66) | FAAHPIK3CAHDAC6HRH3SSTR5 | |
| SCHEMBL3476698 | 0.81 | FAAH (1.00) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL3476876 | 0.81 | FAAH (0.77) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL13436720 | 0.80 | FAAH (0.78) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL3474867 | 0.80 | FAAH (0.69) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL3477435 | 0.80 | FAAH (0.75) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 | |
| SCHEMBL3476435 | 0.80 | FAAH (0.74) | FAAHSSTR5 | |
| SCHEMBL3476299 | 0.79 | FAAH (0.73) | FAAHPIK3CAHDAC6SSTR5RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |