Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.73 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476876 | 0.84 | FAAH (0.77) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL3476698 | 0.84 | FAAH (1.00) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL3475774 | 0.84 | FAAH (0.61) | FAAHRPS6KA2PIK3CAHDAC6TSHR | |
| SCHEMBL13436720 | 0.83 | FAAH (0.78) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL3477435 | 0.83 | FAAH (0.75) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL3477307 | 0.82 | FAAH (0.66) | FAAHPIK3CAHDAC6 | |
| SCHEMBL3476787 | 0.82 | FAAH (0.72) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL13436687 | 0.82 | FAAH (0.59) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 | |
| SCHEMBL3476655 | 0.82 | FAAH (0.69) | FAAHRPS6KA2PIK3CAHDAC6RAB9A | |
| SCHEMBL3477293 | 0.81 | FAAH (0.66) | FAAHRPS6KA2PIK3CAHDAC6SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |