Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472330 | 0.89 | HTT (0.54) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL21820015 | 0.84 | HTT (0.58) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL11588323 | 0.78 | ASAH1 (0.46) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL11586820 | 0.78 | ASAH1 (0.46) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL28309321 | 0.78 | HTT (0.53) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL5858382 | 0.76 | ASAH1 (0.47) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL10503285 | 0.75 | ALDH3A1 (0.62) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL7100805 | 0.74 | ALDH3A1 (0.61) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL7209144 | 0.74 | HSD17B10 (0.52) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL4736616 | 0.73 | SLC9A1 (0.54) | POLBTSHRASAH1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102558067-A | 1-arylsulfonyl-1H-benzimidazole derivative and preparation method and application thereof | UNIV SICHUAN | 2012-07-11 | — | — | CN | claimed |
| CN-105237480-A | 2-trifluoromethyl benzimidazole compound and preparation method thereof | UNIV CHINA THREE GORGES CTGU | 2016-01-13 | — | — | CN | disclosed |
| CN-102558067-A | 1-arylsulfonyl-1H-benzimidazole derivative and preparation method and application thereof | UNIV SICHUAN | 2012-07-11 | — | — | CN | disclosed |
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | BUMHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100286220-A1 | HNF4alpha ANTAGONISTS AND METHODS OF USE | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-11-11 | — | — | US | disclosed |
| US-4474947-A | Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes | BIOSEARCH (US) | 1984-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | HNF4A, NCOA4, NR4A3 | HTT 2121/4885ALDH3A1 865/4885POLB 428/4885 |
| US-20100286220-A1 | HNF4alpha ANTAGONISTS AND METHODS OF USE | HNF4A, NCOA4, NR1H4 | HTT 2191/4885ALDH3A1 530/4885POLB 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.