Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476650 | 0.82 | FAAH (0.63) | FAAHHDAC6PIK3CASSTR5 | |
| SCHEMBL3477409 | 0.82 | FAAH (0.71) | FAAHHDAC6PIK3CAAAK1 | |
| SCHEMBL3477307 | 0.81 | FAAH (0.66) | FAAHHDAC6PIK3CA | |
| SCHEMBL3476787 | 0.80 | FAAH (0.72) | FAAHHDAC6PIK3CASSTR5 | |
| SCHEMBL3475828 | 0.80 | FAAH (0.66) | FAAHHDAC6PIK3CASSTR5AAK1 | |
| SCHEMBL3475819 | 0.79 | FAAH (0.65) | FAAHHDAC6PIK3CAAAK1 | |
| SCHEMBL3478096 | 0.79 | FAAH (0.78) | FAAHHDAC6PIK3CA | |
| SCHEMBL3476959 | 0.79 | FAAH (0.74) | FAAHHDAC6PIK3CASSTR5SSTR1 | |
| SCHEMBL3474437 | 0.79 | FAAH (0.71) | FAAHHDAC6PIK3CASSTR5SSTR1 | |
| SCHEMBL3476698 | 0.78 | FAAH (1.00) | FAAHHDAC6PIK3CASSTR5SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |