Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150473 | 1.00 | CYP4F2 (0.45) | CYP4F2CYP4A11PPARAMEN1KMT2A | |
| SCHEMBL5150487 | 0.85 | UHRF1 (0.37) | CYP4F2CYP4A11MEN1KMT2AUHRF1 | |
| SCHEMBL22070904 | 0.81 | PPARA (0.49) | PPARACYP1A2CYP3A4CYP2C19PPARG | |
| SCHEMBL3370613 | 0.80 | PPARA (0.48) | CYP4F2CYP4A11PPARAPPARGALDH1A1 | |
| SCHEMBL16231402 | 0.78 | UHRF1 (0.46) | MEN1KMT2AUHRF1CCR1CCR5 | |
| SCHEMBL31422488 | 0.77 | CYP4F2 (0.51) | CYP4F2CYP4A11PPARAMEN1KMT2A | |
| SCHEMBL3368880 | 0.76 | CNR1 (0.46) | CYP4F2CYP4A11PPARAMEN1KMT2A | |
| SCHEMBL3231973 | 0.75 | UHRF1 (0.43) | MEN1KMT2AUHRF1CCR1CCR5 | |
| SCHEMBL3475307 | 0.75 | MAP4K4 (0.49) | CYP4F2CYP4A11PPARAMEN1KMT2A | |
| SCHEMBL3374708 | 0.75 | MAPT (0.41) | PPARAMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754188-B2 | Radiolabeled cannabinoid-1 receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080076805-A1 | Acyclic Hydrazides as Cannabinoid Receptor Modulators | MERCK SHARP & DOHME CORP. | 2008-03-27 | — | — | US | disclosed |
| CN-101048368-A | Acyclic hydrazides as cannabinoid receptor modulators | MERCK & CO INC (US) | 2007-10-03 | — | — | CN | disclosed |
| US-20060115425-A1 | Substituted amides | MERCK SHARP & DOHME CORP. | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076805-A1 | Acyclic Hydrazides as Cannabinoid Receptor Modulators | CNR1, CNR2, FAAH | CYP4F2 1765/4885CYP4A11 595/4885PPARA 344/4885 |
| US-20060115425-A1 | Substituted amides | CNR1, CNR2, FAAH | CYP4F2 1449/4885CYP4A11 2098/4885PPARA 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.