Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477643 | 0.80 | FAAH (0.57) | FAAHAPP | |
| SCHEMBL3141145 | 0.80 | PRKCI (0.50) | FAAHAPP | |
| SCHEMBL3477481 | 0.78 | APP (0.60) | FAAHAPPKDM4ENPC1ALDH1A1 | |
| SCHEMBL3476971 | 0.78 | FAAH (0.64) | FAAHAPP | |
| SCHEMBL713750 | 0.78 | ALDH1A1 (0.69) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL712315 | 0.76 | SMN1; SMN2 (0.59) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL3478456 | 0.76 | FAAH (0.72) | FAAH | |
| SCHEMBL3478154 | 0.76 | FAAH (0.53) | FAAHAPP | |
| SCHEMBL3476620 | 0.73 | FAAH (1.00) | FAAH | |
| SCHEMBL3476334 | 0.73 | FAAH (0.95) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |