Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | FAAH | O00519 | 12/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174585 | 0.78 | NPC1 (0.66) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3476128 | 0.78 | FAAH (0.58) | APPFAAHNPC1RAB9AKDM4E | |
| SCHEMBL2633271 | 0.77 | NPC1 (0.64) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL19846146 | 0.77 | NPC1 (0.64) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2688110 | 0.77 | NPC1 (0.55) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL30727501 | 0.76 | NPC1 (0.62) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1913541 | 0.76 | NPC1 (0.62) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1507814 | 0.75 | APP (1.00) | APPFAAH | |
| SCHEMBL31170 | 0.75 | NPC1 (0.81) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL17691814 | 0.74 | NPC1 (0.60) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |