Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309770 | 0.84 | KMT2A (0.94) | KMT2AALDH1A1HTTUSP2KDM4E | |
| SCHEMBL1309772 | 0.84 | KMT2A (0.94) | KMT2AALDH1A1HTTUSP2KDM4E | |
| SCHEMBL1311593 | 0.77 | HSP90AA1 (0.56) | KMT2AALDH1A1MAPTTAAR1PKM | |
| SCHEMBL3478318 | 0.69 | HSP90AA1 (0.54) | KMT2AALDH1A1MAPTTAAR1MAPK1 | |
| SCHEMBL6203929 | 0.68 | SIGMAR1 (0.53) | ALDH1A1HTTKDM4EMAPTTAAR1 | |
| SCHEMBL5594322 | 0.68 | KMT2A (0.58) | KMT2AALDH1A1HTTUSP2KDM4E | |
| SCHEMBL56059 | 0.68 | ADH1B (0.61) | KMT2AALDH1A1KDM4EMAPTTAAR1 | |
| SCHEMBL27503416 | 0.67 | ALDH1A1 (0.45) | KMT2AALDH1A1HTTMAPTTAAR1 | |
| SCHEMBL1311595 | 0.66 | SMN1; SMN2 (0.40) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL1310936 | 0.66 | KMT2A (0.48) | KMT2AALDH1A1HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391614-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | Instytut Chemii Organicznej, Polska Akademia Nauk (PL) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010087727-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2010-08-05 | — | — | WO | disclosed |